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Article summary AI generated Glucocorticoids are commonly used to treat various inflammatory and autoimmune diseases but are associated with significant side effects, necessitating the development of safer alternatives

This review discusses the development of novel antiobesity drugs based on current understanding of energy homeostasis Keywords: Obesity, Pharmacotherapy, Drug targets

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1,000 to 1,200 mg daily, based on body weight less than or greater than 75 kg (it has been recently suggested that the heaviest patients could even benefit from a higher ribavirin dose, up to 1,600 mg daily) and they theoretically require 48 weeks of treatment (Figure 1A) [18 ]

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